Samarium doped biphasic calcium phosphates (Sm doped BCP) powders were synthesized via a two-step process involving a sol-gel and a sintering, and after their microstructre and antibacterial properties were thoroughly investigated. To synthesize Sm doped BCP, calcium nitrate tetrahydrate (Ca(NO3)2·4H2O) as a calcium source and diammonium hydrogen phosphate ((NH4)2HPO4) as a phosphorus source were chosen as the best pair of starting materials. Samarium(III) nitrate hexahydrate (Sm(NO3)3⋅6H2O) was used as a dopant source. The sol-gel process was performed to have good homogeneity and higher crystallinity of particles. The obtained powders were sintered at 1200° C to complete the synthesis of Sm doped BCP powders. The powders were characterized by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), X-ray diffractometer (XRD), Fourier transform infrared (FT-IR), thermogravimetric analysis (TGA), and UVvis spectroscopy. The antibacterial activity of the synthesized Sm doped BCP was confirmed using Gram-negative E. coli and Gram-positive S. aureus. The XRD results detected that Sm doped BCP powders had crystallized hydroxyapatite and β-tricalcium phosphate phases. This situation has revealed that Sm doped BCP powders were successfully synthesized. The morphologies properties of the Sm doped BCP powders exhibited particles with a wholely homogenous distribution. Furthermore, antibacterial results manifested the significance of the Sm doped BCP for use in biomedical applications.
Anahtar Kelimeler: Sm, BCP, Sol-gel, Calcination, Antibacterial properties